Inhibitory Receptor CLEC4a4 is Present in Eosinophils in an Intracellular Reserve and Modulated by IL-5 and Notch 2 Signaling

Arman Kian, Natalie A. Falta, Leigha D. Larsen, and Lisa A. Spencer

Presented at:  

• STEP-UP Research Conference, NIH, Bethesda, MD, Aug, 2024

• **NESS/BSCP conference, Harvard Medical School, Boston, MA, March, 2025

  **Won First Place (out of >70 presenters) in Immunology, Genetics, & Microbiology category!!! Congratulations Arman!

Eosinophils Specialized in Coculture with Esophageal Epithelial Cells and TGF-b Induce Esophageal Fibroblast Activation

Erin Austin, Katie Ly, Evie Nguyen, Shelnna Huynh, and Julia Dunn

Presented at:

• (Dunn) FASEB GI Tract XXI, Banff, Canada, Sept, 2024

• (Austin) Mol Biol Retreat, Winter Park, CO, Nov, 2024

• (Austin) Autumn Immuno Conf, Chicago, IL, Nov, 2024

• (Austin) Child Health Research Day, CHCO, Jan, 25

Local Inflammation Imprints an Unrestrained Tissue-Adapted Phenotype on Intestinal Eosinophils

Leigha D. Larsen, Arman Kian, and Lisa A. Spencer

Presented at:  

• Child Health Research Day, CHCO, Jan, 2025

• Crohn's and Colitis Congress, San Francisco, Feb, 2025

Environmental Drivers of Eosinophil Specialization

Evie Nguyen, Erin Austin, Katie Ly, Shelna Huynh, and Julia Dunn

Presented at:

• (Nguyen) NDiSTEM, Phoenix, AZ, Nov, 2024

• (Dunn) Child Health Research Day, CHCO, Jan, 2025

Etrasimod Treatment of Acute and Chronic Mouse Model of Eosinophilic Esophagitis

Taylor Crue, Leigha Larsen, Devin Dobias, Calies Menard-Katcher, Luke Simerly, Lisa A. Spencer, Joanne C. Masterson, Glenn T. Furuta

Presented at:

• Department of Pediatrics Winter Poster Session, 2024

• **NASPGHAN, Hollywood, FL, Nov, 2024

  **NASPGHAN Poster of Distinction!!!

Physician Utilization of and Perspectives on Esophageal String Testing in Patients with Eosinophilic Esophagitis

Rachel Andrews, Laura Quinn, Maureen Bauer, Stephanie Skirka, Jordan Koplan, Nathalie Nguyen

Presented at:

• Child health research Day, CHCO, Jan 2025

• NASPGHAN, Hollywood, FL, Nov 2024

Phenotypic Changes to Eosinophils during Resolution in a Mouse Model of Eosinophilic Esophagitis

Shelnna Huynh, Allison Dubner, Erin Austin, Evie Nguyen, Katie Ly, and Julia L.M. Dunn

Presented at:

• Digestive Disease Week (DDW), May 2025

Unsedated Transnasal EGD for Evaluation of Celiac Disease, A Single Center Pilot Experience

Julia Sessions, Nathalie Nguyen, Kristen Liu, Michael Joseph, Edwin Liu, and Jacob A. Mark

• NASPGHAN, Chicago, IL, Nov, 2025